Home > News > Using nano-diamond sensors to measure cell thermal conductivity could lead to new cancer treatments

Using nano-diamond sensors to measure cell thermal conductivity could lead to new cancer treatments

wallpapers News 2021-04-27
Using nano-diamond sensors to measure cell thermal conductivity could lead to new cancer treatments
 
A team of scientists from Osaka University, the University of Queensland and the National University of Singapore used tiny nano-diamonds coated with an exothermic polymer to probe the thermal properties of cells. When illuminated with a laser, the sensor acts as both a heater and a thermometer, allowing the thermal conductivity inside the cell to be calculated. The work could lead to new treatments that use heat to kill bacteria or cancer cells. The study was published in Science Advances.
The cell is the basic unit of all living things, and some physical properties, such as thermal conductivity, remain difficult to study in vivo.
 
Now, the team has developed a technique that can determine the thermal conductivity within living cells with a spatial resolution of about 200 nanometers. They created tiny diamonds coated with the polymer polydopamine that both fluoresce and emit heat when illuminated by a laser.
 
Experiments show that the particles are non-toxic and can be used in living cells. When in a liquid or cell, the heat raises the temperature of the nanodiamond. In high thermal conductivity media, nano-diamonds do not become very hot due to rapid heat escape, but in a low thermal conductivity environments, nano-diamonds become even hotter.
Crucially, the properties of the emitted light depend on temperature, so the team can calculate the rate of heat flow from the sensor to the surrounding environment.
The researchers found that "as measured by the hybrid nanosensor, the heat diffusion rate in the cells was several times slower than that in pure water."
 
"In addition to improving thermotherapy for cancer, the potential applications of this work will advance the understanding of metabolic disorders such as obesity," the researchers said. In addition, the tool can also be used for basic cell research, such as real-time monitoring of biochemical reactions.
 

Say something
  • All comments(0)
    No comment yet. Please say something!
Tag: